I'm going to kick-start this community with my favorite Weird West work. Darkwatch had everything I wanted from a Weird Western: a vampire gunslinger shooting monsters at night. Sure, the gameplay could've been better (a lot better) but the world-building was so fun I loved it anyway.

I don't know if I could handle playing the game again today; it got mediocre reviews even when it was released and the game mechanics are even more dated now. But I'll always have a soft-spot for it and would love a sequel in this world.

Here's a trailer showing just how ridiculous the game was.