I have only really used upstream distros (specifically what I've used is debian, open suse, Arch, Gentoo, and nixOS). I've never had audio issues, except when I first started using Gentoo, as I was missing some compile flags.
That being said I only started using Linux 3 years ago.
@WarlordSdocy @ExperimentalGuy
I have the same and opposite issue.
Part of the reason that I am always using #linux is because so much of my workflow these days requires Linux, that when I play something like a #bethesda game (modding them is just less of a hassle on Windows) it just feels wrong and uncomfortable.