Pretty much... as long as you didn't do any custom kernel stuff or driver blacklisting or any other underhood voodoo with the boot system.

I moved my SSD from my old 8th gen Intel laptop to my brand new Zen 4 Framework 16. It was absolutely uneventful. Almost disappointing 😅

I recently did an Intel to AMD switch and still using the same installation with same SSD. I just needed to reconfigure my network name because motherboard is changed though.

If you have a default kernel it should be fine (If you don't know and you haven't installed nvidia drivers you do). I've even moved around between amd and intel without issues.

I swapped the boot drive from a 1st gen i7 machine to a threadripper machine and it worked without any issues. I was using the default kernel on Linux Mint.

If you have any temperature monitoring or custom fan control stuff, you will need to reconfigure it though.

No, unless you did stuff that would lead to you not asking this question.

I've pulled Linux boot drives out of one machine to stick them in a very different machine (e.g. from a 6th gen Intel i7 with an AMD GPU to an AMD 5950X with an NVIDIA GPU) and they almost always just work or require only minor tweaks. Chances are it will be fine.

I compile my kernel with specific cpu optimizations, so i'll just have to recompile a new image. Outside of that, everything is drop-in

I did a similar upgrade last year. I don't recall any problems under Debian. I now have Bluetooth and Wi-Fi, which my old mobo did not support.

Of course, you should be sure to do a full backup.

Exciting! Enjoy the upgrade!

Generic distro kernel? You shouldn't have any problems.

Hand-compiled kernel cooked up with -march=native? You're sticking with AMD, so there should still be no issues unless some instruction got dropped between the old CPU and the new, which almost never happens. You might have to add a kernel module or two for things built into your mobo, nothing serious.

(Hell, I had a Windows 2000 install on a multi-boot system survive an upgrade like that, once upon a time. Just booted perfectly happily on the new hardware.)