Pharmacology - Drug Nerds

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DrugNerds is a community for informed discussion about drug chemistry and pharmacology. It is intended to have a wider focus than the de facto preoccupation with psychoactive drugs in the subreddit of the same name. Content about ALL types of drugs is welcomed and encouraged!

Moderators will not hesitate to ban those who have not read the rules. No warnings are given - if you do not have the initiative to read the rules before posting, you may not post here.

In short, this community is NOT for questions where you need an answer from experts, but for people who have done some research and want a good discussion about the issue in question. You do not have to be trained in pharmacology to post, but you should have a command of basic science.

Rules

  1. No questions needing an answer from experts. Posts which demonstrate a lack of basic understanding of the subject matter, a lack of willingness to investigate on one's own, or a need for answers based on personal drug use or that of family, friends, etc will be removed.
  2. No medical advice, questions about personal drug use, consumption methods, etc. This community is not for asking medical questions, giving medical advice or asking about personal drug use.
  3. ABSOLUTELY NO requesting, hinting or sharing sources for drugs. Naming, linking to, or requesting sources in any context, whether legal or illegal, for any reason, will result in a very long ban.
  4. Posts and questions must contain some degree of research done. While we understand that not everybody is knowledgeable in drugs and pharmacology, we kindly ask that you include some degree of research done. As such, posts based purely on vibes are not allowed, and any questions asked MUST be accompanied by links to the resources uncovered in pre-research.
  5. You must read and understand the rules of the community before participating. First posts which break the rules may result in an immediate ban. You must not encourage rule-breaking posts by responding unless responding to make them aware of the rules.
  6. Don't be an asshole. Treat others with respect. If you try to rules-lawyer this one, expect a ban.
  7. No memes, no stoner / "drug culture" content, and no low-effort content.

founded 19 hours ago
MODERATORS
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Hello and welcome to the threadiverse's pharmacology discussion forum!

If you are familiar with r/DrugNerds on reddit, this is intended to be a very similar community, albeit hopefully with a wider focus. r/DrugNerds tends to be heavily oriented toward discussion of psychoactives and nootropics, whereas I would like DrugNerds to serve people with interests in all subfields of pharmacology.

My hope is that in coming here you will be just as likely to find an article about Rational Drug Design, or a paper about the discovery of a new antibiotic, or a link to an especially pithy Derek Lowe post, as you will be to see a post about a recreational drug or nootropic.

Reading the rules is mandatory and breaking them in your first post may result in an immediate ban, so head to the sidebar now and scan them over!

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tl;dr: researchers used Structure-Based Drug Design to derive a new antibiotic from florfenicol which shows effectiveness against a number of antibiotic-resistant bacteria.

Structure-based drug design (SBDD) aims to design small-molecule ligands that bind with high affinity and specificity to pre-determined protein targets.