somehow I guess it's still not common knowledge yet but basically everything that doesn't need a kernel anti cheat will work. or maybe not newer dotnet crap but usually those aren't games. mods and cheats are hit and miss and require some setup, but mostly work anyway. for most games protondb lists what works with and without tinkering but even some of the stuff listed as not working actually does in my experience. pcgamingwiki info is still usefull for a lot fixes to known problems on all platforms.

amd graphics should work out of the box but sometimes the newest cards have issues for a while after release. Any modern distro will not need extra setup as long as the maintainers aren't too far behind.

nvidia requires manual intervention for most distros but some have installers that default to nvidia graphics. expect some jank, there's a lot of weird shit that can go wrong with kernel modules not matching the kernel version among other things.

other hardware can also be problematic and people like myself who have been selecting hardware specifically for linux compatibility may give the idea that nothing is wrong.

I recommend nobara or bazzite for gaming setups that will require little to no addititonal work to play games and most hardware that is possible to work just working out of the box or with a guided config.

If you want to go with a non gaming oriented distro (trust me don't unless you do it on a spare comp or vm for experimentation), then debian, or mint debian, one of the easy arch installers even, but don't do ubuntu. Weird shit will inevitability happen eventually and the old guides and crap ai articles with outdated information from the mail order ubuntu cd days will make it way too confusing to fix unless you are a web search sorceror.