Also 10s of billions is still insignificant for any power, transport, or healthcare infrastructure in the scheme of things -

Bullshit. If you can get the same amount of reliable power by just slapping up some solar panels, wind turbines, and batteries, then obviously the cost is not insignificant.

That sentence shows that you really aren't thinking about this as a practical means of power generation. I've found that most fission boosters don't so much like actual nuclear power, but the idea of nuclear power. It appeals to a certain kind of nerd who admires it from a physics and engineering perspective. And while it is cool technically, this tends to blind people to the actual cold realities of fission power.

There's also a lot of conspiratorial thinking among the pro-nuclear crowd. They'll blame nuclear's failures on the superstitious fear of the unwashed ignorant masses or the evil machinations of groups like Greenpeace. Then, at the same time, they'll ignore the most bone-headedly obvious cause of nuclear's failure: it's just too fucking expensive.