Yeah, life support being off or at reduced power would mean carbon dioxide build up and it would probably get a bit sweaty, but you can survive for quite a long time in a sealed room, especially with how much spare space is in Star Trek rooms.

Unless life support includes something like "shields that keep all the air in" or something.

I agree with the theme of the post, but some of the examples need more work, possibly at the expense of being less quippy