I start with default settings, but with rail world ores. Then I bump up the water coverage a bit and tweak the scale to get huge islands. I love setting the goal of clearing my entire starter continent of biters, pushing my walls forward bit by bit until I don't need them anymore.

Then I eventually run out of one resource or another, and need to bridge to a new continent, and start the process all over again ^^

Technically, this world generation is "easier" since you could just clear a continent then not have to worry about pollution anymore, but I try to minimize pollution anyway to save my forests and lakes. I actually haven't triggered a single biter attack from pollution in my current 300+ hour playthrough...