There are numerous ways to deal with it, depending on the specific application and use-case. For some, there's an open-source alternative that, while not 100% similar in every aspect imaginable, does offer basically the same functionality (LibreOffice for MS Office Suite, Thunderbird for various email clients, Firefox or just Chromium for Google Chrome). For others, you can use an emulator (WINE, for example). For games specifically, Steam offers an emulator that works for most games (Proton); in fact, all the games I've tried worked. Then, there's the very last option, which is using a virtual Windows machine within Linux. I mention it last because I honestly haven't found many cases where I absolutely needed to do this, and because the set-up is rather "involved", shall we say. But if you're using Adobe Suite stuff then, yeah, you basically got no choice there.

Would you mind listing some of the essential programs that you use so we can get a better idea what your workflow is?