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this post was submitted on 10 Dec 2023
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It depends on the disability, the magic, and the DM's interpretation, I suppose. Lesser restoration is kind of a cure-all, gets rid of disease, poison, blindness, deafness, and paralysis, and 'disease' in particular might cover a pretty wide swath. Greater restoration can end effects that reduce ability scores or hit point maximums, which might include chronic conditions or congenital birth defects not directly linked to a disease. Regeneration can grow back missing body parts. Anything that these spells don't cover, Wish (and Divine Intervention) almost certainly would, but you'd be hard-pressed to find someone who could and would cast it.