999
xkcd #2867: DateTime
(imgs.xkcd.com)
Alt text:
It's not just time zones and leap seconds. SI seconds on Earth are slower because of relativity, so there are time standards for space stuff (TCB, TGC) that use faster SI seconds than UTC/Unix time. T2 - T1 = [God doesn't know and the Devil isn't telling.]
Epoch is your friend, or use UTC. At least that's my layman reasoning. I have no challenges working with DateTime except when I don't know the underlying conditions applied from the source code.