You said it yourself, "this is about testosterone and anesthetic sensitivity." (edit: it did before an edit) So why use sex as an abstraction over the real variable if it isn't relevent? This isn't about trans activism any more than it is about "PCOS activism". People are just pointing out that conditions such as PCOS, having XXY chromosomes, and hormone therapy treatment affect the testosterone levels (and thus anesthetic sensitivty) independent of sex. A more clear and correct statement would just talk about testosterone levels. The inference that women tend to have lower testosterone levels shouldn't be anything more than a side note; it's relevance isn't title-worthy.