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Helldivers 2 anti-cheat is a nightmare for Steam Deck players
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Works for me and I run Garuda which is basically a desktop equivalent to SteamOS.
I just played for like three hours solid. It crashed a few times when I was configuring it before I played the tutorial but other than that it's been fine.
Please consider submitting a record for the game on ProtonDB regarding your config, if you haven't already. That would likely be helpful for others that are running into issues.
Good to hear that it is working well.