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Google tries to defend its Web Environment Integrity
(techreport.com)
This is a most excellent place for technology news and articles.
It would be difficult. Your operating system, the browser, and the website's code would have to be compliant to pass the WEI check
Let's say you use a non-compliant OS (linux), or a non-chromium browser, or use userscripts, in all three cases you are locked out of the website.