I've sort of just accepted it. I work in a niche position in a software company that's in a niche sector and while people do depend on me for their livelyhoods, I wouldn't say the products I produce are, in the grand scheme of things, meaningful. What I do only exists as a job in the 20th and 21st centuries and humans got on just fine before that.

I instead find meaning in my hobbies and out of work activities. My job, while pretty meaningless in my mind, does pay me enough to allow me to have a good life outside of work. I don't need my job to be meaningful, I just need it to not suck.