that's the joke
Science Memes
Welcome to c/science_memes @ Mander.xyz!
A place for majestic STEMLORD peacocking, as well as memes about the realities of working in a lab.
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This is a science community. We use the Dawkins definition of meme.
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Memes
Miscellaneous
I mean, she's not wrong.
Came here to say this.
She's technically correct, the best kind of correct.
Wow they got our bodies addicted to mrna and now if we take them out we will die??!!!??
Vax hacks
Certain temperatures can completely denature viruses like HIV and covid. Anything above 600 degrees should do the trick.
600 degrees Celsius or Fahrenheit?
I'm not sure it matters, bluntly.
Kelvin could do the trick too.
Rankine might be a little more iffy though...
First one, then the other.
Does it matter which one is first?
Yes if you want to have nice caramelization instead of just burned skin.
that's the joke, no?
Yeah, and you can't spread diesease while you're dead, can you Simon?
unfortunately you can, just not as effective as living people do.
Still "greatly reduce".
The person doesn't know how viruses work
I mean killing a major portion of all viruses will stop transmission. So would killing the person. Exactly how drinking bleach kills the virus.
I think the commenter in the picture was wooshed
Also, it's bothering me that it's not immediate.
If he was going to be wooshed, he could at least get the details right...
I think a healthy body could survive a single instantaneous disappearance of current mRNA, as long as the mechanisms to create more mRNA remain functional. All cells would just respond to new conditions more slowly and less effectively for a few minutes to hours, leaving the body vulnerable to disbalancing conditions such as infections. Some cells would die but most of them can be replaced in days.
On the other hand, deleting DNA (and thus preventing the creation of RNA) cannot be survived. A great exploration of such scenario is in the No More DNA chapter in What If? by Randall Munroe: the syptoms would be like eating an Amanita mushroom such as the "Destroying Angel", whose amatoxin prevents DNA transcription, or acute gamma irradiation. The patient is fine for a few hours (or less with a theoretical DNA wipe), then start exhibiting cholera-like symptoms (vomiting, abdominal pain, diarrhea), then they start to feel better. However, at that point, since cells can't divide, immune system collapse or systemwide organ failure is inevitable.
But isn't that what the first poster is playing on? It would certainly lower the chance of transmitting a virus
i thought that was the point
Narrator: it is.
~~Narrator~~ Morgan Freeman: it is.
Who is to say that the narrator isn't Morgan Freeman?
Waitaminute. Are you telling me there are stupid people on the internet talking about things they don't understand?
The internet is the worst thing we've ever done to ourselves. I mean, it was fine at first. But we didn't have enough cynicism to account for what corporations would do with it and that's, sadly, our own fault for being too naive.
This is a joke. Have you considered the possibility that you are the stupid person in this case?
We had really high hopes and big dreams for the Internet when it was conceived.
We ended up with social networks that steal and sell you information without your knowledge, and without any compensation to you, and "AI" slop for chat bots, and forum posts and pictures and even video now....
This is not what the Internet was made for.
I don't know if it's true, but it feels like the Internet was better when it was limited to enthusiasts and people in higher education.
Letting every idiot post every word that comes to mind for the whole world to see was probably a mistake.
Look up "eternal september" on wikipedia. You're not wrong at all.
🌈 classism 🌈
Yeah, you're probably not wrong, sorry.
Plenty of rich people are shitting up the internet, though.
The internet is still okay, just don't use any corporate social network and generally ignore everything made by corporations.
We also underestimated the number of idiots in the population. Or their ability to find little niches in which to congregate.
Think of the illnesses you could avoid if you removed your blood!
I actually wonder how long it would take to notice if all your mRNA stopped working.
I don't think neuron action potentials rely directly on mRNA, so I think you'd be able to keep thinking for a bit, and probably moving your muscles too. The closest comparable thing is people that received massive radiation doses (can't make new RNA out of shredded DNA) and in those cases it takes a bit before you start melting.
I think it would be comparable to situation where all mRNA is suddenly unusable, ie protein synthesis can't run at all. This would be something like ricin or diphteria toxin poisoning, but instead of being limited to gastrointestinal lining it's spread all over. I'd guess hours to days before anything visible starts happening (symptoms only start to appear when deficit in new protein synthesis becomes noticeable; all protein already made continues to work for sone time)
Don't destroying angel mushrooms basically stop your body from making proteins? That's roughly the same net effect as RNA stopping working so it should give you a pretty good approximation.
This is how amatoxins from mushrooms kills you. They shut down mRNA synthesis in the liver.
The amanitin toxin is heat stable, remaining toxic whether eaten raw or cooked. The mechanism of action of amatoxin is by inhibiting RNA polymerase, causing disruption of transcription of mRNA. As a result, hepatocytes cannot synthesize key protein coding genes, leading to the disintegration of nucleoli and pathologically centrilobular hepatic necrosis. This leads to the insidious onset of liver failure over 48 hours. Late onset (more than six hours after ingestion) of vomiting and watery diarrhea occur due to the second component in some of these mushrooms which are phallotoxin. Lepiota species lack phallotoxins so may not have the onset of vomiting and diarrhea until after 12 hours post-ingestion, or may just present with symptoms of liver failure at 24 hours post ingestion.
https://www.ncbi.nlm.nih.gov/books/NBK431052/
Wow ok 😬