Dust sources are:
- Leaky air ducts: air ducts leak up to 11% on both the supply and return lines for a total of ~20% whenever your central air turns on. Yum fiberglass insulation!
- Shed skin flakes: humans drop 1.5 lbs of skin a year. Dusty!
- Dryers agitate clothes while heating them. Yum lint!
- Shoes track in dust. Yum dirt.
You could consistently clean the air with a hepa filter that you clean regularly.
You could install a hrv system with a hepa filter on the intake duct while being anal about no leaks in the ducts. Then set it to make positive internal air pressure.
You could get a vaccume and mop roomba robot.
You could take off your shoes before coming into the house.
You could try to seal all your existing ducts.
Between all these suggestions, I think your dust would become negligible.
Fun.