Mark Lawrence has several trilogies that fit into this genre. They're fantasy books but the setting/universe is based on science fiction.

Series that I've read and recommend:

Broken Empire

Holy Sister

Red Queens War

I found them all an enjoyable mix of dark/grim fantasy with a good mix of humor. These series all tend to follow an anti-hero or in Broken Empire's case you could argue it's a villain protagonist given just how unsavory a character Jorg is. Even still I found myself liking and rooting for that bastard.

Stephen King’s Dark Tower series. Mix of cyberpunk post-apocalyptic parallel universes with science so deep it’s magic.

(Trying not to give away too many spoilers!)

As a bonus, there’s an extended reading list which ties the Dark Tower into books and short stories from King’s universe.

The Broken Earth series is really original and well written.

Someone else suggested N.K. Jemisin’s Broken Earth series, which is also an unusual take on the post-apocalyptic and survivalism stuff that a lot of people are into these days.

Wait, Gormenghast has Science fiction? When does that show up? I only read the first book so far and don't remember a lot.

Mark Lawrence's "Book of the Ancestor" and "Book of the Ice" series.

• The Captain by Will Wight
• The Shadows of Dust by Alec Hutson
• Portal to Nova Roma by J.R. Mathews
• Starship's Mage by Glynn Stewart

• The City We Became and The Broken Earth series by N.K. Jemisin.
• Light From Uncommon Stars by Ryka Aoki
• Remote Control by Nnedi Okorafor