Carnelian

Well, if you’re feeling philosophical I think you’d first need to address your presupposition that life has or is meant to have any meaning whatsoever.

Like, according to who? And how did they determine that? Would you be sad if it turns out there isn’t any underlying meaning?

This was a very heartfelt post, thank you for writing it up. I see a lot of parallels here in the way my parents thought about me and my siblings growing up.

I think the issue though is one of trajectory. It seems like more and more people are struggling to make it. The thought of working extra to pay for something nice is fading somewhat as working “extra” becomes a necessity just to afford food and housing. There’s a huge upsurge of people going into debt currently via financing their groceries for example.

We should develop robust safety nets to prevent this. We have the resources to make decent groceries and shelter available to everyone. We need to push back hard against every attempt to resist making it actually happen

I think they’re talking about thoughts, as you and I might call them

Quit six years ago now! More worth it than I could have believed

Thank you for created wired headphone content!

No I get what you’re trying to say, the problem is your arguments make no sense

The number of musicians on the stage is irrelevant. I’ve seen plenty of shows with a single guitarist. They aren’t costing other musicians anything by doing their own thing

You also are trying to make the point that people “suddenly” care just because it’s AI even though you reference nearly 50 year drama in the same post

Yea there are parallels between the AI slop situation and other technological advances (invention of the camera, moving pictures, typewriters, and so on) which you are trying to illustrate but your illustrations are misguided. There’s a clear difference, and your strategy of throwing artists under the bus isn’t going to accomplish anything. Not that you seem to actually want to accomplish anything other than making some grand proclamation about society

To be honest, reading thru the study and poking at some of the discussions about it online, it seems to not be remotely saying what people are saying it’s saying lol.

Like they weren’t able to find many of the results they expected in actual human samples compared to the mice. They also found that slower weight loss seemed to correspond with fewer and less severe epigenetic changes.

That second point there was never really expanded on beyond a throwaway statement, but it jumped out at me because the humans studied received bariatric surgery. Which causes massive weight loss very quickly. They even cited that as a potential confounding variable.

It’s also not really about “fat cells multiplying” at all, but rather how a collection of dozens of different factors differ between never obese and formerly obese samples, and only at the two year mark after a weight loss intervention.

Their own conclusion is that “they have not proven” their findings have anything to do with weight regain. This is then bizarrely and immediately followed by what can only be described as an unprompted advertisement for Ozempic, along with speculative musing that further study is needed to determine if it could be used to “erase or diminish” the epigenetic memory (despite semaglutide being unrelated to the experiments and appearing nowhere else in the paper?). Interestingly enough, there’s also an extant conflict of interest statement linking one of the researches to several pharmaceutical companies, including Novo Nordisk

All in all, it strikes me as nothing more than yet another case of bad science reporting. With people kind of going in with preconceived notions, glossing over all of the details, and emerging with snippets taken out of context (body remembers being fat! It changes your genetics!). Lo and behold all the online discussion centers around just the provocative headline and the speculative sections of the paper.

It seems like the researches even deliberately tried to use language to bait this type of response from the general public (although this is now just speculation on my part). In summary, I am unpersuaded by the available evidence. Thank you however for linking it! There is a lot of other interesting info in there

Righteous, thank you! I’m in the muck right now at work but I’ll give it a read when I can

Sorry, I’m not sure what you mean?

DJs never performed with bands? Disc Jockey. They’ve always played pre-recorded music.

Synthesizers also aren’t used to replace musicians. It’s a totally different sound. That’s like saying the piano replaced the upright bass because it can hit all the same notes. Just not how that works.

Also why throw shade at synths at all? They’re very far from fake instruments, if you’ve ever sat down to actually understand them and listen to synthesizer dominant music outside of the 80s pop you dislike so much

Seconded, I flipped to youtube then flipped back to check. This is top tier monkey content, people!

Thank you, no rush! If so could you please reply in a new comment so I get a notification?

Gotcha, yeah and thanks once again for the discussion. What I’m looking for basically is just evidence for the claim posted above us, specifically that “it is a fact that weight loss results in lifelong ravenous hunger due to fat cell signaling”

Scientists all the time come out with reviews and proposals that ultimately fizzle out without supporting evidence. So before I am able to believe any specific claims I need to see that it’s an actual scientific finding rather than just something tentative that has caught headlines (like I said, it happens all the time).

Since you like reading studies in general, for your own amusement I would suggest investigating the claim “cooking rice with coconut oil, then leaving it in the fridge overnight, will reduce the calories absorbed by your body by half!”

It’s a total and blatant piece of misinformation based on a chain of bad news reports made about a study that claimed something totally different, and was subsequently never confirmed. Yet I have met people in real life who swore by the method (even though they struggled to lose weight regardless of this supposed calorie cutting “hack”).

The weight loss space in general is totally flooded with this type of misinfo which is why I get so particular about it. Thank you again!