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I don't mean that literally, of course, but metaphorically. Back when Prozac first hit national consciousness here in the US in the early 90s there was a huge backlash against it, much like the one we're seeing against the GLP/GIPs.

Every magazine had a special issue with a bottle of pills lit by scary, dramatic lighting for a cover. There was a constant discourse of hysteria and pearl clutching like: "you'll have to be on it forever!", "it doesn't really fix anything!", "it's so expensive!", "what if they give it to children?!?", "oh no the side effects!". Every self appointed expert had a reason you shouldn't take it: "you don't need it, you just need God", "you just need to get tough", "it's a cop out for the weak", etc, etc. Even many therapists and psychiatrists spoke against it, often more afraid for their jobs than anything else, "what if we fix everything with a pill, what does that mean for psychiatry?"

And now, 30 years later we have a much better understanding of anti-depressants. They are a common prescription and much of society accepts them the same way we accept people being on statins, insulin or ibuprofen. They didn't destroy psychiatry, make everyone become mindless drones or create a bunch of psychopaths. And they became a whole lot more affordable.

On the other hand, Prozac itself would be an odd prescription today as there are much better, more targeted medications with fewer side effects.

I strongly believe the same thing will happen with semaglutide and tirzepatide, but probably much faster due to the much larger number of potential patients. In ten years the new family of weight loss drugs will be commonly used and accepted by society, but they probably won't be semaglutide or tirzepatide but rather some new, more targeted meds that are cheap and have far fewer side effects.

But that doesn't mean I'm going to wait a decade to lose this weight.

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40s M, 5'11, SW 255, GW 200?

I've been overwieght almost my entire life. One summer in elementary school my weight shot way up and it's been high ever since. I've been on every diet, have always done sports, hit the gym regularly, and am generally active, but I've never been able to keep it off long, or even make it down to a "normal" BMI, generally floating somewhere between overweight and obese. Over the last two years, my weight has started climbing at a pound or two a month and I haven't been able to stop it.

I took my first dose of semaglutide tonight, after trying to get a hold of it for the last six months. My insurance denied me said I had to join Weight Watchers for six months. Then, two months ago I was laid off. But, a couple of my friends have had success with one of the compounding pharms, so I though I'd give them a try. My partner also did the same thing, and took their first dose last week. Here's hoping that this is the change I've needed!