wandersong is a super simple game that she might be able to play. You play a pacifist bard who just is naive, friendly to a fault. The bard is a male, but the villain, supporting cast, it's quite diverse with some strong females cast in. It's got a pretty good story and a lot of sesame street level lessons on life in there too. Even starts a conversation on what strength truly is. Totally something you should look at.

Slime rancher is another super chill, might actually be able to play herself, game where you do play as a female protaganist, but much lighter on plot than wandersong. You basically farm cute adorable slimes and it's genuinely pretty addictive and super relaxing after a shitty day.

Mirror's Edge you play as a female protagonist. Plot might be a bit steep for her.

If you haven't played through portal 1 or 2 yet, I bet it could be fun. Glados is silly, Chell (who you play but doesn't talk) is female and she can help you with the puzzles a bit.