To me, the biggest danger is people being “scared to talk about” a subject. This applies both to the comedian thinking of making a joke about X demographic, and also the member of X demographic unsure whether to voice how bad the joke made them feel.

Say the second guy condemns the comedian with an ultimate mic drop moment, so the comedian just shuts up and only talks the subject with an echo chamber of bigots who’ve had similar experiences.

Or, the second guy shuts up forever, and when the first guy runs for president on a platform of stopping the orphan crushing machine, the second guy thinks “Man, fuck that guy” and votes against him.

There’s definitely a much better median where they bring up the discontent in a gentle prompt - only escalating if they’re ignored. It takes two though, and the comedian would have to be okay with saying “Okay, I apologize.” That part is hard; with so much anonymous interaction now it feels rare for anyone to humbly admit fault.