To add to the blog post, if you use user scripts, utilize your manager's blacklist and learn REGEX.

If needed, use Group Policy, Regedit or .plists on macOS to blacklist domains to prevent an extension from running on them. As an example, I use Shutup.css to block comments online, but on something like Lemmy, I want to see comments as that's primarily how content is created and adding it to my extension domain blacklist prevents the extension from running on the website or any lemmy domains.