No, it won't be blocked.
That being said, it will be handicapped.
https://www.spacebar.news/chrome-ad-blocking-manifest-v3-ublock-origin/
Safari doesn't have uBlock Origin at the moment AFAIK; it was discontinued. uBlock Origin on Firefox will continue using MV2 which allows for better extension/list updating.
Honestly, Fuck Steve Huffman.
I'm excited to see where Lemmy, Mastodon and the Fediverse go as I believe that's what Aaron Swartz wanted Reddit to be when it merged with Infogami; a user curated platform about anything, and a great source of knowledge.