this post was submitted on 05 Sep 2025
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[–] yucandu@lemmy.world 16 points 18 hours ago (2 children)

Here's a few, not sure if they're peer-reviewed but one is a meta-analysis. Important to note which journals these are published in, since less reputable journals will happily publish a lawsuit-seeking falsified study in exchange for money.

Anyway I haven't read these, here you go:

https://pmc.ncbi.nlm.nih.gov/articles/PMC6138494/

In conclusion, on the basis of these studies, only weak associations between paracetamol exposure and neurodevelopmental issues have been identified, and no causal link can be inferred.

2018 The British Pharmacological Society

https://academic.oup.com/aje/article-abstract/187/8/1817/4980325

Acetaminophen use during pregnancy is associated with an increased risk for ADHD, ASD, and hyperactivity symptoms. These findings are concerning; however, results should be interpreted with caution given that the available evidence consists of observational studies and is susceptible to several potential sources of bias.

  1. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health

https://pmc.ncbi.nlm.nih.gov/articles/PMC6822099/

Cord biomarkers of fetal exposure to acetaminophen were associated with significantly increased risk of childhood ADHD and ASD in a dose-response fashion. Our findings support previous studies regarding the association between prenatal and perinatal acetaminophen exposure and childhood neurodevelopmental risk and warrant additional investigations.

2019 American Medical Association

Okay yeah now I'm concerned.

[–] BlameTheAntifa@lemmy.world 7 points 14 hours ago (1 children)

Okay yeah now I’m concerned.

The sum of those studies is effectively little to nothing. We all know that correlation is not causation and these correlations are weak and logically problematic.

Instead, take a look at this one, which not only hypothesizes a cause, but used that hypothesis to form a treatment that worked so well it seemed almost miraculous.

https://pmc.ncbi.nlm.nih.gov/articles/PMC5497533/

[–] troed@fedia.io 9 points 18 hours ago

Three weeks ago (interesting timing), meta study:

Our analyses using the Navigation Guide thus support evidence consistent with an association between acetaminophen exposure during pregnancy and increased incidence of NDDs. Appropriate and immediate steps should be taken to advise pregnant women to limit acetaminophen consumption to protect their offspring’s neurodevelopment.

https://ehjournal.biomedcentral.com/articles/10.1186/s12940-025-01208-0