So (TW: TMI), I have had very loose stool since starting SSRI's. And when I have to go, I have to go! (One day I sneezed and did what my mother very patiently taught me not to do 43 years earlier.) I also get hot flashes at the same time every day (I'm biologically male), and have started needing to nap in the mid afternoon in order to function the rest of the day. On the plus side I no longer deal with feelings of ennui or that life is pointless, and my stress levels aren't quite as high, which is nice