That's a very defensive response. You're mocking the above poster because they "can't deal with physics" but you seem to be neglecting biology yourself.

Driving something like 400km would take a good 4-6 hours depending on traffic. As a flesh and blood human you need to at least stop for the toilet, you should eat something to keep your energy levels up and you must always stay hydrated. Sure, you can power your body through that, but you can also power your body through 48 hours without sleep or an entire KFC bucket of chicken all to yourself - just because you can doesn't mean you should or that it's healthy. The difference in this case is that fatigue can lead to deaths, not just your own but whatever poor sucker you happened to drive into because you have been driving for 6 hours straight and lost concentration at just the wrong time.

Please do come back and claim that you don't lose concentration and that you don't need to stop every few hours because your reaction times and concentration levels are just fine. There isn't a human on the planet that can make such a claim. Again: just because you can does not mean you should.