Additionally, the Burke's superstructure clearly has much more 'stuff' on it than a Karakurt does, so in addition to being much larger, a Arleigh Burke is going to be much more capable at various tasks.

It has 90 missile cells compared to 8, anti submarine ability (compared to none), multiple different radar sets and triple fire control systems, 2 helicopters, and it'll go 4000 miles vs 2000.

Apart from both of them floating (hehe) there's really no comparison.