I stumbled upon this response blog post to people missing the point of Lena and it’s perfect:

Oh boy, what if there was a maligned sector of human society whose members were for some reason considered less than human? What if they were less visible than most people, or invisible, and were exploited and abused, and had little ability to exercise their rights or even make their plight known?

That's real! That actually happens! You can name four groups of people matching that description without even thinking. We don't need to add some manufactured debate about fictitious, magical uploads to these real scenarios. They are already terrible!

and now I’m trying to brainstorm ways to slip a link to awful.systems into qntm’s inbox that don’t look insane