Just don't get hit /s

Use terrain to lose agro on enemies. Know enemy vision.

Play smart, don't take risks.

If an enemy could be behind that door, it probably is.

Have failsafes: phase shift, blind dart, blink stone, artifact recharge for rouge cloak...

I usually don't play this challenge 😉

But, 1.5 years ago people were doing 9 challenge runs with a strategy that was called wandrunner.

It is a rogue/freerunner that uses the wand one gets from the wand maker quest to dump all updates into. The freerunner has with his skill a boost on speed and dodging. That's where the wand as a ranged weapon comes into play.

The key is basically don't get hit (I know, I know, easier written then done) but it's true and it's where ranged weapons come into play. A huntress build can help here as well.

I’m honestly working on this challenge now. It requires changing your strategy from reducing damage via armor upgrades to avoiding damage at all costs. Avoiding damage is really hard to do, but increasing evasion by using cloth/leather armor and/or ring of evasion helps.

My successes with this one have been with mage and huntress. Both allow you to create a build with high damage at range, minimizing the chances to get hit. The rogue’s free runner class is also a good option.

Monk has an ability that lets her charge her ability way faster when using T1 stuff. Maybe you can use T1 armor with Monk to do the run.

I would ways run warrior, since he has a t3 ability hold fast, which gives additional armor that isn't reduced by the challenge.

Never played that challenge, but I guess +20 Ring Of Evasion? Or +20 Ring of Haste?