I really disliked how The Sopranos ended!
Van Halen's Jump comes to mind first, although my reason is just how overplayed it was.
I suppose one that I disliked a long while for a different reason is Bring Me to Life by Evanescence. I later remembered it was playing on the radio in my mother's car when we arrived at the hospital after I drove her and my sister into the city to say goodbye to my dying father. He died a few hours later.
I thought it was a reference to Tea Party.