SneerClub

it's a guess of what can be abstracted away and what has to remain. i'd just add that evolutionarily, peptide signalling is older than synapses so these, or something that works like these, probably can't be just left out of the picture, and there's a couple of processes that seem important that depend on them (you can live normal life while packed full of naloxone, which blocks activity of opioid peptides, but this probably won't work with, say, orexin which is important for sleep/wake cycle)