I am rewatching My Name is Earl at the moment. It is still great in my opinion.

If you want closure, here's what was planned for the ending:

Garcia said the finale would begin with Earl getting stuck on a really hard list item, frustrated that he would never finish crossing everything off his list. "Somebody shows up at our motel door," added Suplee recently, "finds us at the bar, and starts to make amends to Earl for something." Earl would then question where the man got such an idea and "goes back and finds all these people who have lists, who are out there trying to do good, and it all comes back to him. He was the beginning of this." Garcia concluded, "Earl eventually realizes that his list started a chain reaction of people with lists and that he’s finally put more good into the world than bad. So at that point he was going to tear up his list and go live his life. Walk into the sunset a free man. With good karma.