Ublock Origin is enough as blocker (It's so complete in terms of filters. also it's recommended by Mozilla, and it's very light). Also Decentraleyes for some third-party contents. Other blockers do the same (they usually use the same blocking lists, too). I only have these two, along with setting Firefox tracking protection to Strict. I guess it's enough. (Though, you can see UBO wiki to have more advanced blockings.)