Use the "Kinoite-main-Nvidia"-image from universal-blue.org. Sounds exactly like what you're looking for, since you mentioned KDE, Pipewire, Wayland, and so on.

• uBlue is an improvement of the regular Atomic (Silverblue, Kinoite, etc.) version of Fedora. It includes some QoL tweaks ootb, like drivers (also Nvidia), auto updates, etc.
• It isn't a distro of itself, just tweaked and directly from the official Fedora image.
• Fedora Atomic is great, but you would have to layer your Nvidia stuff in the official version, which isn't ideal.
• The uBlue-Nvidia-image is well tested and won't break (hopefully), at least not as often as the official image. And if it does, the maintainers would know, since their own and thousands of other installs would break too, and they can fix it easily, since every install is the same. You can always just select the version from yesterday for example if it breaks, and your OS will work exactly as before, it will always work reliable.
• For every spin (Gnome, Cinnamon, KDE, Sway, etc.) there's also a Nvidia version. You can easily rebase to another variant without reinstalling in case you want to