I play guitar and bass right handed. Especially for bass, it feels more natural to fret with my dominant hand and use the index and pluck with my right hand. That being said, I play fingerstyle most of the time and I'm not good with a pick, so playing leftie might be better for picking hand dexterity.

I play left-handed. Been playing for 30 years. I also taught my right-handed sister to play left-handed.

I’m left handed and play right handed. 99% of the guitars out there are right handed. It’s so much easier to find gear for righties. I also like the idea of being able to be at a party or a beach or a jam or a whatever and get handed a guitar and be able to play it, rather than have to say “sorry, I’m a leftie.” Playing right handed hasn’t felt weird or anything, it’s been fine.

Now, that being said, I know of several lefties who play right handed guitars… literally just learned how to play it upside down. They still can get handed a right handed guitar and they can just deal with it. It’s pretty wild to watch them play, but they manage. I also know a left handed fiddle player who similarly plays right handed fiddles but just does it backwards. Wild stuff.