I've had some trouble getting my modded save to load at all, to load completely, to play dialogue correctly, and not to crash when fast traveling. Even after purging all my mods I've had problems. What I've learned: Don't use the lari launcher. Just use the exe from your game files, or the dx11 exe if that doesn't work (although for me skipping the launcher already solved my problem). If you're using a mod manager you can launch over those as well. Larian will probably hotfix over the next few days, but until then this is a nice workaround.