If you read the Wikipedia entry, then the song was supposed to be named "set us on fire" but was misheard as "sex on fire", they found it funny and ran with it. And it's about one of the band members partners.
So no, it's not about STIs. If you want more meaning given the lyrics, then someone's genitals is sometimes referred to as their "sex" so "your sex is on fire" could mean your genitals are hot. Or, "on fire" can mean good at something so it could mean they're good at sex.
A friend of a friend slept with the lead singer of Kings of Leon and allegedly he gave her gonorrhoea so it turned out to be quite literal
Your “sex” is your pubes, and “on fire” is a rash. He’s saying you have VD.
I thought it was a song about good sex, like something being "fire" is good, it's hot. Flames are often associated with love and passion. So I thought it was a song about being good at hot sex.
But the burning sensation of certain STIs would also make sex burn like fire.
🤷♀️
What do I do if Bob is indeed my uncle, but it's not alright?
Call him Robert
What does ‘your sex is on fire mean’?
It's about STIs - get a bit of natural yogurt on it and it should be fine.
A casual place for banter and anything that doesn't fit in anywhere else.
Have chat and a natter. Talk about anything and everything.
Keep it casual.
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